Treating Osteoarthritic Joints Using Dextrose Prolotherapy and Direct Bone Marrow Aspirate Injection Therapy,

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Treating Osteoarthritic Joints Using Dextrose Prolotherapy and Direct Bone Marrow Aspirate Injection Therapy

Osteoarthritis is a chronic, progressive disease of the articular joints, and to date, has no cure or effective longterm treatment. Objective: To determine if bone marrow prolotherapy (BMP), a combined treatment protocol employing separate injections of hypertonic dextrose prolotherapy and bone marrow aspirate, would be effective as a means of reducing joint pain and improving function in osteo...

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Rationale for Using Direct Bone Marrow Aspirate as a Proliferant for Re- generative Injection Therapy (Prolotherapy)

Adult mesenchymal stem cells (MSCs) obtainable from autologous bone marrow aspirates have generated tremendous interest in the medical and scientific communities in the last two decades and are currently being investigated by a of interested physicians for use in point-of-care stem cell therapies due to their great potential to differentiate into multiple cell lineages such as bone, cartilage, ...

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Regenerative Injection Therapy with Whole Bone Marrow Aspirate for Degenerative Joint Disease: A Case Series

Regenerative therapeutic strategies for joint diseases usually employ either enriched concentrates of bone marrow-derived stem cells, chondrogenic preparations such as platelet-rich plasma, or irritant solutions such as hyperosmotic dextrose. In this case series, we describe our experience with a simple, cost-effective regenerative treatment using direct injection of unfractionated whole bone m...

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Dextrose prolotherapy for recalcitrant coccygodynia.

PURPOSE To present the results of dextrose prolotherapy undertaken for chronic non-responding coccygodynia in 37 patients. METHODS 14 men and 23 women (mean age, 36 years) with chronic coccygodynia not responding to conservative treatment for more than 6 months were included. 27 of them had received local steroid injections. A visual analogue score (VAS) was recorded for all patients before a...

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Randomized, prospective, placebo-controlled double-blind study of dextrose prolotherapy for osteoarthritic thumb and finger (DIP, PIP, and trapeziometacarpal) joints: evidence of clinical efficacy.

OBJECTIVES To determine the clinical benefit of dextrose prolotherapy (injection of growth factors or growth factor stimulators) in osteoarthritic finger joints. DESIGN Prospective randomized double-blind placebo-controlled trial. SETTINGS/LOCATION Outpatient physical medicine clinic. SUBJECTS Six months of pain history was required in each joint studied as well as one of the following: g...

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ژورنال

عنوان ژورنال: The Open Urology & Nephrology Journal

سال: 2014

ISSN: 1874-303X

DOI: 10.2174/1876539401407010001